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NFL Leaders |
Defensive Tackles
| Rank | Name | Team | G | TK | Sacks | Sack-Yds | Int | Fum | PD |
| 1 | Z. Brown | Buf | 16 | 149 | 4.0 | 17.0 | 1 | 2 | 4 |
| 2 | C. Kirksey | Cle | 16 | 143 | 2.5 | 16.0 | 0 | 0 | 3 |
| 3 | P. Brown | Buf | 16 | 135 | 1.0 | 5.0 | 0 | 1 | 1 |
| 4 | P. Posluszny | Jax | 16 | 133 | 1.5 | 17.0 | 1 | 0 | 3 |
| 5 | Z. Orr | Bal | 15 | 130 | 0.0 | 0.0 | 3 | 1 | 5 |
| 6 | B. McKinney | Hou | 16 | 129 | 5.0 | 31.0 | 0 | 1 | 2 |
| 7 | J. Cyprien | Jax | 16 | 126 | 1.0 | 2.0 | 0 | 1 | 4 |
| 8 | T. Smith | Jax | 16 | 118 | 1.0 | 0.0 | 2 | 0 | 8 |
| 9 | K. Alonso | Mia | 15 | 115 | 0.0 | 0.0 | 2 | 1 | 4 |
| 10t | K. Dansby | Cin | 16 | 114 | 1.0 | 0.0 | 0 | 0 | 6 |
| 10t | L. Timmons | Pit | 16 | 114 | 2.5 | 22.0 | 2 | 1 | 5 |
| 12 | J. Collins | Cle | 15 | 112 | 3.0 | 25.0 | 2 | 2 | 3 |
| 13 | A. Williamson | Ten | 16 | 104 | 2.0 | 14.0 | 1 | 1 | 1 |
| 14 | M. Smith | Oak | 15 | 103 | 0.0 | 0.0 | 1 | 2 | 3 |
| 15 | V. Burfict | Cin | 11 | 101 | 2.0 | 11.0 | 2 | 1 | 8 |
| 16 | D. Davis | Cle | 16 | 99 | 2.0 | 20.0 | 0 | 1 | 2 |
| 17 | T. Davis | Den | 16 | 97 | 0.5 | 2.5 | 0 | 1 | 3 |
| 18 | D. Harris | NYJ | 15 | 94 | 0.5 | 3.0 | 0 | 0 | 2 |
| 19t | C. Mosley | Bal | 14 | 92 | 0.0 | 0.0 | 4 | 1 | 8 |
| 19t | L. Ryan | NE | 16 | 92 | 1.0 | 12.0 | 2 | 1 | 11 |
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